Binding Probability

#Physics

$\displaystyle P_{b}=\frac{\frac{c}{c_{0}}e^{-\beta \Delta \varepsilon}}{\frac{c}{c_{0}}e^{-\beta \Delta \varepsilon}+1}$

• The probability of binding for a ligand with concentration $\displaystyle c$ relative to $\displaystyle c_{0}$ to a receptor with binding energy minus free energy $\displaystyle \Delta \varepsilon$ and [coldness] $\displaystyle \beta$