Catalytic Efficiency

$\text{Catalytic Efficiency}=\frac{k_{\text{cat}}}{K_m}$

• This is the rate that ES becomes EP regardless of the concentration of substrate
• This value times $[E]$ is the slope of the line Michaelis-Menten equation when $[S]\ll K_m$
• $k_{\text{cat}}$ is the turnover number
• $K_m$ is the Michaelis Constant