~7 nm

  • Allows cells to move by lamellipodia ~3 µm/min
  • ADP-actin dissociates at the pointed end (i.e. negative end), gets phosphorylated (sped up by profilin) to ATP-actin, and adds to the barbed end (positive end)
  • Cofilin may break up the microfilaments to increase the number of open ends of microfilaments

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